Botulinum toxin as a therapeutic agent
Identifieur interne : 003D10 ( Main/Exploration ); précédent : 003D09; suivant : 003D11Botulinum toxin as a therapeutic agent
Auteurs : Joseph K. C. Tsui [Canada]Source :
- [ 0163-7258 ]
Abstract
Botulinum toxin is a presynaptic neuromuscular blocking agent that, when injected intramuscularly in minute quantities, can produce selective muscle weakness. This property is employed therapeutically to provide symptomatic relief in conditions related to excessive muscle activities in strabismus, blepharospasm, hemifacial spasm, cervical dystonia, spasmodic dysphonia (adductor type), and jaw closing dystonia. It is investigational for a long list of medical conditions. It is a marketed drug in a number of countries in the world, but its use has only been approved by different regulatory agencies for use in a limited number of conditions. The long-term effects, appropriate dose for children, and in pregnancy, and maximum dose without causing toxicity remain unclear.
Url:
DOI: 10.1016/S0163-7258(96)00091-5
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002527
- to stream Istex, to step Curation: 002527
- to stream Istex, to step Checkpoint: 001720
- to stream Main, to step Merge: 004400
- to stream Main, to step Curation: 003D10
Le document en format XML
<record><TEI wicri:istexFullTextTei="no"><teiHeader><fileDesc><titleStmt><title>Botulinum toxin as a therapeutic agent</title><author><name sortKey="Tsui, Joseph K C" sort="Tsui, Joseph K C" uniqKey="Tsui J" first="Joseph K. C." last="Tsui">Joseph K. C. Tsui</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:7AB0A595F1E80A027E34CF3C299126831D7C9EEA</idno><date when="1996" year="1996">1996</date><idno type="doi">10.1016/S0163-7258(96)00091-5</idno><idno type="url">https://api-v5.istex.fr/document/7AB0A595F1E80A027E34CF3C299126831D7C9EEA/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002527</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002527</idno><idno type="wicri:Area/Istex/Curation">002527</idno><idno type="wicri:Area/Istex/Checkpoint">001720</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001720</idno><idno type="wicri:doubleKey">0163-7258:1996:Tsui J:botulinum:toxin:as</idno><idno type="wicri:Area/Main/Merge">004400</idno><idno type="wicri:Area/Main/Curation">003D10</idno><idno type="wicri:Area/Main/Exploration">003D10</idno></publicationStmt><sourceDesc><biblStruct><analytic><author><name sortKey="Tsui, Joseph K C" sort="Tsui, Joseph K C" uniqKey="Tsui J" first="Joseph K. C." last="Tsui">Joseph K. C. Tsui</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>Neurodegenerative Disorders Centre, Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia V6T 2B5</wicri:regionArea><wicri:noRegion>British Columbia V6T 2B5</wicri:noRegion></affiliation></author></analytic><series><idno type="ISSN">0163-7258</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0163-7258</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Botulinum toxin is a presynaptic neuromuscular blocking agent that, when injected intramuscularly in minute quantities, can produce selective muscle weakness. This property is employed therapeutically to provide symptomatic relief in conditions related to excessive muscle activities in strabismus, blepharospasm, hemifacial spasm, cervical dystonia, spasmodic dysphonia (adductor type), and jaw closing dystonia. It is investigational for a long list of medical conditions. It is a marketed drug in a number of countries in the world, but its use has only been approved by different regulatory agencies for use in a limited number of conditions. The long-term effects, appropriate dose for children, and in pregnancy, and maximum dose without causing toxicity remain unclear.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Tsui, Joseph K C" sort="Tsui, Joseph K C" uniqKey="Tsui J" first="Joseph K. C." last="Tsui">Joseph K. C. Tsui</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003D10 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003D10 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:7AB0A595F1E80A027E34CF3C299126831D7C9EEA
|texte= Botulinum toxin as a therapeutic agent
}}
| This area was generated with Dilib version V0.6.29. |  |